Difenacoum is a second generation indirect anticoagulant rodenticide that inhibits the vitamin K dependent steps in synthesis of clotting factors. It belongs to the 4-hydroxycoumarin class of anticoagulants and is a pesticide intended to control commensal rodents (Norway rat, roof rat, and house mice) in and around buildings, stored products and inside of transport vehicles. In many countries, it has been marketed as a “second generation anticoagulant”, a designation that it shares with Brodifacoum, Bromadiolone, and Difethialone.